Dr. Kamath’s began his research career by investigating hyperglycemia caused by the indiscriminate use of insecticides, where he demonstrated the adverse effect of organophosphate insecticides such as dimethoate and dichlorvos in disturbing pancreatic function in rats and rendering them sensitive to the oral glucose tolerance test. Further in his postdoctoral research career he was associated with a laboratory at Wayne State University; dedicated to understanding the signaling events leading to insulin secretion in beta cells. There he examined the role of histidine phosphatase and prenyl-transferase in glucose stimulated insulin secretion. Thereafter as a Fixed-term Faculty, he was associated with Dr. McKee’s research group at Central Michigan University and was involved in delineating and understanding the basic biochemical pathways of nucleoside metabolism and the extent of damage caused by antiretroviral compounds employing gene expression analysis. He taught at the Department of  Foundational Sciences, College of Medicine, Central Michigan University, Mount Pleasant, MI, USA. trained in various pedagogy methods that involved  facilitating the small group of medical students in problem based learning (PBL), integrated community experiences (ICE), writing cases for case based learning (CBL) and developing team based learning modules in several organ systems (Gastro Intestinal, Musculoskeletal/Dermatology, Reproduction and Hematology/Oncology). Helped develop new integrated medical curriculum at the newly started College of Medicine, Central Michigan University. 

Publications

• Ward, A. S., Hsiung, C., Kesterson, D. G., Kamath, V. G., & McKee, E. E. (2022). Entecavir Competitively Inhibits Deoxyguanosine and Deoxyadenosine Phosphorylation in Isolated Mitochondria and the Perfused Rat Heart. Journal of Biological Chemistry, 298 (5). https://doi.org/10.1016/j.jbc.2022.101876
• Towheed, A., Hietanen, C. L., Kamath, V. G., Singh, L. N., Ho, A., Engelstad, K., Cornett, K., Montes, J., & De Vivo, D. (2021). Hypotonia-Cystinuria 2p21 Deletion Syndrome: Intrafamilial Variability of Clinical Expression. Annals of Clinical and Translational Neurology, 8 (11), 2199-2204. https://doi.org/10.1002/acn3.51464
• Wollocko, H. et al (2019 June 7). Reaction oxygen species of organ systems and disease: a systematic review. 1st Place for Poster presented at Orange Regional Medical Center 5th Annual Poster Competition, Middletown, NY.
• Kamath, V. G. (2017). Is it time to start using mitochondrial DNA copy number as an indicator of health and diseases? Cancer Studies and Molecular Medicine Open Journal, 3(2), 21-22.
• Mukherji, A., Onikoyi, O., & Kamath, V. G. (2015). Pancreas: Do all roads lead to mitochondria? Pancreas Open Journal, 1(1), 1-3.

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