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Kathleen DiCaprio, PhD

Assistant Professor of Microbiology, Department of Basic Biomedical Sciences

  • Office: 230 West 125th Street, Room 428
  • Campus:
    Touro College of Osteopathic Medicine - Harlem
  • Phone:
    (646) 981-4758
  • Email:
    kathleen.dicaprio@touro.edu

Dr. DiCaprio teaches Medical Microbiology as well as masters and undergraduate courses related to infectious diseases. She earned her BS in Biochemistry from The College of Saint Rose and her PhD in Pathology from Uniformed Services University of the Health Sciences. Her prior research focused on studying pathogenesis of maximum containment (Biosafety-level 4) viruses such as Ebola and Marburg viruses in nonhuman primate models. Her research efforts have contributed to the development of potential vaccines and therapeutics against these deadly viruses and such work has been profiled in numerous publications and press releases.

Her longstanding interests in infectious diseases and public health brought her to New York City where she worked for the NYC DOHMH Public Health Laboratory. During her time with NYC Health Department she assisted in laboratory and emergency response affairs during the H1N1 Influenza 2009 outbreak in NYC.

Education/Training

PhD, Pathology
Uniformed Services University

BA, Biochemistry
The College of Saint Rose

Courses Taught

Microbiology and Immunology
Human Health and Behavior

Areas of Research

Infectious Disease and Public Health
Educational Outcomes

Selected Publications

1. Geisbert TW, Jones, S, Fritz EA, Shurtleff AC, Geisbert JB, Liebscher R, Grolla A, Stroher U, Fernando L, Daddario KM, Guttieri MC, Mothe BR, Larsen T, Hensley LE, Jahrling PB, Feldmann H. Development of a new vaccine for the prevention of Lassa Fever. 2005 PLoS Med 2(6):0537.

2. Jones SM, Feldmann H, Stroher U, Geisbert JB, Fernando L, Grolla A, Klenk HD, Sullivan NJ, Volchkov VE, Fritz EA, Daddario KM, Hensley LE, Jahrling JB, Geisbert TW. Live attenuated recombinant vaccine protects nonhuman primates against Ebola and Marburg viruses. 2005 Nat. Med. 11(7):786-90

3. Geisbert TW, Hensley LE, Kagan E, Yu EZ, Geisbert JB, Daddario-DiCaprio K, Fritz EA, Jahrling PB, McClintock K, Phelps JR, Lee AC, Judge A, Jeffs LB, Maclachlan I. Postexposure Protection of Guinea Pigs against a Lethal Ebola Virus Challenge is conferred by RNA Interference. 2006 J Infect Dis Jun 15; 193(12):1650-7

4. Daddario DiCaprio K, Geisbert TW, Stroher U, Geisbert JB, Grolla A, Fritz EA, Fernando L, Kagan E, Jahrling PB, Hensley LE, Jones SM, Feldmann H. Postexposure protection against Marburg hemorrhagic fever with recombinant vesicular stomatitis virus vectors in non-human primates: an efficacy assessment. 2006 Lancet 367(9520):1399-404

5. Daddario DiCaprio K, Geisbert TW, Geisbert JB, Stroher U, Hensley LE, Grolla A, Fritz EA, Feldmann F, Feldmann H, Jones SM. 2006. Cross Protection against Marburg Virus Strains using a Live Attenuated Recombinant Vaccine. 2006 J. Virol. 80(19):9659-66

6. Neumann G, Geisbert TW, Ebihara H, Geisbert JB, Daddario-DiCaprio KM, Feldmann H, Kawaoka Y. Proteolytic Processing of the Ebola Virus Glycoprotein in not critical for Ebola Virus replication in nonhuman primates. 2007 J. Virol. 81(6):2995-8

7. Feldmann H, Jones SM, Daddario-DiCaprio KM, Geisbert JB, Stroher U, Grolla A, Bray M, Fritz EA, Fernando L, Feldmann H, Hensley LE, Geisbert TW. Effective Post-Exposure Treatment of Ebola Infection. 2007 PLoS Pathog. 13(1):e2

8. Rubins, KH, Hensley L, Wahl-Jensen V, Daddario-DiCaprio KM, Young H, Jahrling P, Brown P, Relman D, Geisbert T. The Temporal Program of Peripheral Blood Gene Expression in the Response of Non-human Primates to Ebola Hemorrhagic Fever. Genome Biology. 2007 Aug 28;8(8):R174 .

9. Larsen T, Stevens EL, Davis KJ, Geisbert JB, Daddario-DiCaprio KM, Jahrling PB, Hensley LE, Geisbert TW. Pathologic findings associated with delayed death in nonhuman primates experimentally infected with Zaire Ebola virus. 2007 J Infect Dis. 196 Suppl 2:S323-S328

10. Geisbert TW, Daddario-DiCaprio KM, Geisbert JB, Young HA, Formenty P, Fritz EA, Larsen T, Hensley LE. Marburg virus Angola infection of rhesus macaques: pathogenesis and treatment with recombinant nematode anticoagulant protein c2. 2007 J Infect Dis. 196 Suppl 2:S372-S381

11. Hensley LE, Stevens EL, Yan SB, Geisbert JB, Macias WL, Larsen T, Daddario-DiCaprio KM, Cassell GH, Jahrling PB, Geisbert TW. Recombinant human activated protein C for the postexposure treatment of Ebola hemorrhagic fever. 2007 J Infect Dis. 196 Suppl 2:S390-S399

12. Markotic A, Hensley L, Daddario K, Spik K, Anderson K, Schmaljohn C. Pathogenic hantaviruses elicit different immunoreactions in THP-1 cells and primary monocytes and induce differentiation of human monocytes to dendritic-like cells. 2007 Coll Antropol. Dec;31(4):1159-67

13. Geisbert T, Daddario-DiCaprio K, Geisbert J, Jones S, Hensley L, Feldmann H. Recombinant vesicular stomatitis virus vector mediates postexposure protection against Sudan Ebola hemorrhagic fever in nonhuman primates. 2008 J Virol. Jun;82(11):5664-8

14. Geisbert T, Daddario- DiCaprio K, Lewis MG, Geisbert J, Grolla A, Leung A, Paragas J, St. Claire M, Lennox M, Smith M, Jones S, Hensley L, Jahrling P, Feldmann H. Ebola hemorrhagic fever vaccine based on replication-competent vesicular stomatitis virus is well tolerated and protects immunocompromised SHIV-infected nonhuman primates. 2008 Plos Pathogens Nov;4(11):e1000225

15. Geisbert TW, Daddario-DiCaprio KM, Geisbert JB, Reed DS, Feldmann F, Grolla A, Stroher U, Fritz EA, Hensley LE, Jones SM, Feldmann H. Vesicular stomatitis virus-based vaccines protect nonhuman primates against aerosol challenge with Ebola and Marburg viruses. 2008 Vaccine Dec 9;26(52):6894-900

16. Geisbert TW, Geisbert JB, Leung A, Daddario-DiCaprio KM, Hensley LE, Grolla A, Feldmann H. Single Injection vaccine protects nonhuman primates against Marburg virus and three species of Ebola virus. 2009 J Virol Apr 22

17. Lessler J, Reich N, Cummings D, New York City Department of Health and Mental Hygiene Swine Influenza Team. Outbreak of 2009 Pandemic Influenzaa A (H1N1) at a New York City School. 2009 NEJM Dec 31;361(27):2628-2636

18. Geisbert TW, Daddario-DiCaprio KM, Hickey AC, Geisbert JB, Mattapallil JJ, Chan YP, Wang L, Hensley LE, Smith MA, Bossart KN, Broder CC. Development of an acute and highly pathogenic nonhuman primate model of Nipah virus infection.. PLoS One. 2010 May 18;5(5):e10690

19. Lisa E Hensley, Mark A Smith, Joan B Geisbert, Elizabeth A Fritz, Kathleen M Daddario-DiCaprio,Tom Larsen and Thomas W Geisbert. Pathogenesis of Lassa Fever in Cynomolgus Macaques. Journal of Virology. 2011 May 6;8:205.

BOOK CHAPTERS
1. Daddario-DiCaprio K, Stern R, Afify A. Idenitification of Cancer Stem Cells for Surgical Pathology: Profiles of hyaluronana, hyaluronan synthases, hyaluronidases, and receptor variants. SUBMITTED in Tech Publishing

2. Wahby A, Daddario-DiCaprio K, Stern R. Hyaluronan Inside and Outside of Skin. M. Loden and HI Maibach (eds). Springer Verlag, Heidelberg, 2011